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Comparative Effectiveness.
Comparative effectiveness, defined as how treatments perform in a real-world clinical situation, is an important complement to efficacy and safety results from randomised clinical trials. Clinical effectiveness can be estimated using clincal hard outcomes, cause specific mortality, laboratory measurements and health care costs.
Clinical hard outcome
Most comparative effectiveness studies stem from type 2 diabetes where novel glucose lowering drugs have been compared to other glucose lowering drugs like DPP4i or any other glucose lowering drug.
Health care costs
Following comparative hard outcome effectiveness analyses, it is also important for health care providers to understand how these results translate into differences in health care costs
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